ironjustice
2011-04-20 13:25:58 UTC
Red meat and colon cancer: Should we become vegetarians, or can we
make meat safer?
Meat Science
Denis E. Corpet, a,
a Université de Toulouse, ENVT, INRA, UMR1331 Toxalim, BP-87614, 23
Capelles, F-31076 Toulouse, France
Received 8 March 2011; revised 7 April 2011; accepted 11 April
2011. Available online 17 April 2011.
Abstract
The effect of meat consumption on cancer risk is a controversial
issue. However, recent meta-analyses show that high consumers of cured
meats and red meat are at increased risk of colorectal cancer. This
increase is significant but modest (20-30%). Current WCRF-AICR
recommendations are to eat no more than 500 g per week of red meat,
and to avoid processed meat. Moreover, our studies show that beef meat
and cured pork meat promotes colon carcinogenesis in rats. The major
promoter in meat is heme iron, via N-nitrosation or fat peroxidation.
Dietary additives can suppress the toxic effects of heme iron. For
instance, promotion of colon carcinogenesis in rats by cooked, nitrite-
treated and oxidized high-heme cured meat was suppressed by dietary
calcium and by α-tocopherol, and a study in volunteers supported these
protective effects in humans. These additives, and others still under
study, could provide an acceptable way to prevent colorectal cancer.
Keywords: Red meat; processed meat; safer meat; colon cancer;
epidemiology; heme iron
Tel.: + 33 561 193 982; fax: + 33 561 491 263.
doi:10.1016/j.meatsci.2011.04.009
Copyright © 2010 Published by Elsevier Ltd.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
make meat safer?
Meat Science
Denis E. Corpet, a,
a Université de Toulouse, ENVT, INRA, UMR1331 Toxalim, BP-87614, 23
Capelles, F-31076 Toulouse, France
Received 8 March 2011; revised 7 April 2011; accepted 11 April
2011. Available online 17 April 2011.
Abstract
The effect of meat consumption on cancer risk is a controversial
issue. However, recent meta-analyses show that high consumers of cured
meats and red meat are at increased risk of colorectal cancer. This
increase is significant but modest (20-30%). Current WCRF-AICR
recommendations are to eat no more than 500 g per week of red meat,
and to avoid processed meat. Moreover, our studies show that beef meat
and cured pork meat promotes colon carcinogenesis in rats. The major
promoter in meat is heme iron, via N-nitrosation or fat peroxidation.
Dietary additives can suppress the toxic effects of heme iron. For
instance, promotion of colon carcinogenesis in rats by cooked, nitrite-
treated and oxidized high-heme cured meat was suppressed by dietary
calcium and by α-tocopherol, and a study in volunteers supported these
protective effects in humans. These additives, and others still under
study, could provide an acceptable way to prevent colorectal cancer.
Keywords: Red meat; processed meat; safer meat; colon cancer;
epidemiology; heme iron
Tel.: + 33 561 193 982; fax: + 33 561 491 263.
doi:10.1016/j.meatsci.2011.04.009
Copyright © 2010 Published by Elsevier Ltd.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk