RainForest
2010-06-15 06:32:51 UTC
Reposted from
http://www.topicalinfo.org/forum/topic.asp?TOPIC_ID=729
The Australian Blushwood tree Hylandia dockrillii as a possible source of a
cancer treatment received some widespread TV publicity on the Australian
Channel 7 Sunday night program on June 13 2010.
http://current.com/news/92088221_possible-cancer-cure-found-in-blushwood-shrub.htm
The applications are far wider than skin cancer and the substance has had
wide testing on other cancers in animals, with apparently excellent success.
It is planned to distribute the drug among Australian vets, which may make
it more accessible to people in need, only for their sick cats of course! We
must at all costs avoid the sick and dying obtaining any relief without
first having their wallets evacuated. Those writhing in their death agony of
cancer with only months to live need also to be protected from the
possibility of horrendous side effects such as mild nausea, allergic
reactions or other terrors that might befall them with drugs tried only on
animals.
The observation that rainforest marsupials spit out seeds after eating the
fruit of a certain plant led to the company's lead compound, EBC-46.
Scientists at EcoBiotics learned that the unpalatable seeds contain an
inflammatory agent that made the animals' tongues swell. They isolated the
active ingredient, a diterpene ester, which belongs to a new class of
chemicals.
EBC-46 shows anticancer properties against basal and squamous cell
carcinomas, melanoma, and head and neck tumours, Delco reports. The active
ingredient in EBC-46 is easily purified from a ubiquitous plant species that
can be quickly grown on plantations. The company is developing a GMP process
to insure commercial quantities of the drug for future investigations.
EBC-46 is a protein kinase C regulator that initiates apoptosis of tumor
cells and causes a local inflammatory reaction that recruits the body's
neutrophils to attack the tumor. When injected into incurable soft tissue
sarcoids, nasopharangeal cancers, and oral malignant melanomas in horses,
dogs, and sheep, EBC-46 destroyed the tumors and healing was evident in
about two weeks, Delco reports. The positive animal results "don't guarantee
that EBC-46 will work in people," he adds, "but it's promising." EcoBiotics
plans to file an investigational new drug application for EBC-46 within a
year.
Given that the discoverers of this plant's capabilities lodged patent
applications in 2006 this is not that new, but already on other forums
people are asking where to get the seeds.
One possible outcome is that the discovery will never be developed but the
company and its patents if any are granted will be bought ought by big
pharma and never come to market. Note that Peplin an Australian company in
Brisbane which developed a skin cancer treatment from Euphorbia peplus
(radium weed) (there is a thread on these forums about it) was taken over on
the Australian stock exchange in November 2009 for around $269 Million by a
large international pharmaceutical company.
Ecobiotics may well suffer the same fate, and the knowledge could be hidden.
This is the great evil of people being able to take patents on essentially
natural processes. So it is important to spread the knowledge of this plant
as widely as possible and for people to obtain the seeds and grow it.
The full contact details including the registered address is in the public
domain in its patent applications under the name Qbiotics Limited. They may
have since changed the name to Ecobiotics, but the Australian patent
application in about 2006 lists Qbiotics Ltd Yungaburra QLD 4884 Australia .
The location of a number of Hylandia dockrillii trees growing in the
rainforest hinterland near Cairns in Danbulla State Forrest, near lake
Tinaroo and in the Wooroonaroo National park is recorded with detailed GPS
coordinates in the National Herberium in Canberra and the data can be
accessed at this URlL of the Global Biodiversity facility.
http://data.gbif.org/occurrences/searchWithTable.htm?c[0].s=20&c[0].p=0&c[0].o=13241275&c[1].s=19&c[1].p=0&c[1].o=100.0E,36.0S,180.0E,4.0N
{that's all one URL above but it does not work to click on, copy and paste
the whole thing]
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712020 233653
Specimen 09/10/1961 17.25°S, 145.66°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712021 249837
Specimen 04/04/1972 17.3299°S, 145.75°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712022 249839
Specimen 04/04/1972 17.3299°S, 145.75°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 303761 256827
Specimen 29/04/1971 17.6599°S, 145.66°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712023 257906
Specimen 29/11/1973 17.4099°S, 145.75°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712025 285788
Specimen 12/03/1975 17.3299°S, 145.75°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712029 547438
Specimen 02/09/1980 17.5799°S, 145.7°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712027 547440
Specimen 17/03/1977 17.5799°S, 145.61°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712028 560042
Specimen 17/12/1980 17.5799°S, 145.73°E Australia View
Hylandia dockrillii Harvard University Herbaria A Arnold Arboretum 106145
Specimen 17.6667°S, 145.667°E
A photo supposed to be the foliage of Hylandia dockrillii is at
Loading Image...
There should be some better pictures, please post URL if you find them.
I have plotted these on a detailed topographic map and most are close to
roads or 4WD tracks and indicate the trees have a fairly wide range in the
area. The tree records date from the 1970's to 2002. There are more along
the Palmerston Highway SE of the crossing of the North Beartrice River. The
information suggests it should not be hard to find some trees growing in the
wild.
Apparently locals are growing the trees in anticipation of commercial
production, and the patent application information suggests this is not a
new discovery but that work was well advanced in 2006 with an even then good
understanding of the biochemistry. The recent Channel 7 Sunday night
publicity has only given it a more widespread airing.
I have no idea as to the reliability of the following, but other information
I have found on the net suggests the active ingredient is in the seeds and
that the substance can be "fairly easily extracted", which may refer to
extraction as a tincture in alcohol as a guess.
This suggests that some experiments using such a tincture on skin cancers
like Basal Call or solar kerotosis would be fairly easy for people to do
If anyone living in the Cairns area can obtain the seeds and distribute some
it would be a service to mankind to help thwart the over commercial
exploitation of this natural resource, or worse still the total suppression
of the treatment.
The company plans to eventually sell the drug patents to a big multinational
pharma company, and make money from selling out in this way which is clearly
outlined in the investor presentation on the company website.
http://www.qbiotics.com/?gclid=CIuykNL_nqICFQcYewodnxa8yA#//
Thus there will be no cheap or widespresd access to this treatment, but just
another rip off with the drug being sold for many thousands of dollars a
dose.
An effective dose is 3mg and the company has stockpiled 12,000 doses for
trials, which it values at betweem 3 and 5 million dollars, but has not
decided on the commercial marketing cost for vetinary applications.
The company CEO states that the active ingredient is a "major component" of
the seed of the plant (which she refers to by the name "Fontania" (phonetic
spelling from the audio on a film clip) but which news sources state to be
the Blushwood and the photo of the seeds on the company website look like
Blushwood seeds.
It is further stated in Qbiotics promotional literature that the active
ingredient is able to be easily isolated, however if it is a major component
of the seed, and from the dosage used 3mg, it may not need to be actually
isolated at all to be effective. Hence my earlier comment that a tincture in
say 60% alcohol of the seeds may be a simple and effective treatment?
It is applied both topically and injected into solid tumors with dramatic
results. See the company website above.
Any one around Cairns with a half dead dog cat or horse, want to gather up
some seeds, soak them in alcohol, and apply the tincture to to an external
tumor or inject a small quantity into a solid tumor? With an animal thats
going to die of cancer anyway soon what have you got to loose?
And there can't be much harm in anyone trying such a tincture on solar
keritosis or Basal cells and see what happens?
http://www.topicalinfo.org/forum/topic.asp?TOPIC_ID=729
The Australian Blushwood tree Hylandia dockrillii as a possible source of a
cancer treatment received some widespread TV publicity on the Australian
Channel 7 Sunday night program on June 13 2010.
http://current.com/news/92088221_possible-cancer-cure-found-in-blushwood-shrub.htm
The applications are far wider than skin cancer and the substance has had
wide testing on other cancers in animals, with apparently excellent success.
It is planned to distribute the drug among Australian vets, which may make
it more accessible to people in need, only for their sick cats of course! We
must at all costs avoid the sick and dying obtaining any relief without
first having their wallets evacuated. Those writhing in their death agony of
cancer with only months to live need also to be protected from the
possibility of horrendous side effects such as mild nausea, allergic
reactions or other terrors that might befall them with drugs tried only on
animals.
The observation that rainforest marsupials spit out seeds after eating the
fruit of a certain plant led to the company's lead compound, EBC-46.
Scientists at EcoBiotics learned that the unpalatable seeds contain an
inflammatory agent that made the animals' tongues swell. They isolated the
active ingredient, a diterpene ester, which belongs to a new class of
chemicals.
EBC-46 shows anticancer properties against basal and squamous cell
carcinomas, melanoma, and head and neck tumours, Delco reports. The active
ingredient in EBC-46 is easily purified from a ubiquitous plant species that
can be quickly grown on plantations. The company is developing a GMP process
to insure commercial quantities of the drug for future investigations.
EBC-46 is a protein kinase C regulator that initiates apoptosis of tumor
cells and causes a local inflammatory reaction that recruits the body's
neutrophils to attack the tumor. When injected into incurable soft tissue
sarcoids, nasopharangeal cancers, and oral malignant melanomas in horses,
dogs, and sheep, EBC-46 destroyed the tumors and healing was evident in
about two weeks, Delco reports. The positive animal results "don't guarantee
that EBC-46 will work in people," he adds, "but it's promising." EcoBiotics
plans to file an investigational new drug application for EBC-46 within a
year.
Given that the discoverers of this plant's capabilities lodged patent
applications in 2006 this is not that new, but already on other forums
people are asking where to get the seeds.
One possible outcome is that the discovery will never be developed but the
company and its patents if any are granted will be bought ought by big
pharma and never come to market. Note that Peplin an Australian company in
Brisbane which developed a skin cancer treatment from Euphorbia peplus
(radium weed) (there is a thread on these forums about it) was taken over on
the Australian stock exchange in November 2009 for around $269 Million by a
large international pharmaceutical company.
Ecobiotics may well suffer the same fate, and the knowledge could be hidden.
This is the great evil of people being able to take patents on essentially
natural processes. So it is important to spread the knowledge of this plant
as widely as possible and for people to obtain the seeds and grow it.
The full contact details including the registered address is in the public
domain in its patent applications under the name Qbiotics Limited. They may
have since changed the name to Ecobiotics, but the Australian patent
application in about 2006 lists Qbiotics Ltd Yungaburra QLD 4884 Australia .
The location of a number of Hylandia dockrillii trees growing in the
rainforest hinterland near Cairns in Danbulla State Forrest, near lake
Tinaroo and in the Wooroonaroo National park is recorded with detailed GPS
coordinates in the National Herberium in Canberra and the data can be
accessed at this URlL of the Global Biodiversity facility.
http://data.gbif.org/occurrences/searchWithTable.htm?c[0].s=20&c[0].p=0&c[0].o=13241275&c[1].s=19&c[1].p=0&c[1].o=100.0E,36.0S,180.0E,4.0N
{that's all one URL above but it does not work to click on, copy and paste
the whole thing]
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712020 233653
Specimen 09/10/1961 17.25°S, 145.66°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712021 249837
Specimen 04/04/1972 17.3299°S, 145.75°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712022 249839
Specimen 04/04/1972 17.3299°S, 145.75°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 303761 256827
Specimen 29/04/1971 17.6599°S, 145.66°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712023 257906
Specimen 29/11/1973 17.4099°S, 145.75°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712025 285788
Specimen 12/03/1975 17.3299°S, 145.75°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712029 547438
Specimen 02/09/1980 17.5799°S, 145.7°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712027 547440
Specimen 17/03/1977 17.5799°S, 145.61°E Australia View
Hylandia dockrillii Australian National Herbarium (CANB) CANB 712028 560042
Specimen 17/12/1980 17.5799°S, 145.73°E Australia View
Hylandia dockrillii Harvard University Herbaria A Arnold Arboretum 106145
Specimen 17.6667°S, 145.667°E
A photo supposed to be the foliage of Hylandia dockrillii is at
Loading Image...
There should be some better pictures, please post URL if you find them.
I have plotted these on a detailed topographic map and most are close to
roads or 4WD tracks and indicate the trees have a fairly wide range in the
area. The tree records date from the 1970's to 2002. There are more along
the Palmerston Highway SE of the crossing of the North Beartrice River. The
information suggests it should not be hard to find some trees growing in the
wild.
Apparently locals are growing the trees in anticipation of commercial
production, and the patent application information suggests this is not a
new discovery but that work was well advanced in 2006 with an even then good
understanding of the biochemistry. The recent Channel 7 Sunday night
publicity has only given it a more widespread airing.
I have no idea as to the reliability of the following, but other information
I have found on the net suggests the active ingredient is in the seeds and
that the substance can be "fairly easily extracted", which may refer to
extraction as a tincture in alcohol as a guess.
This suggests that some experiments using such a tincture on skin cancers
like Basal Call or solar kerotosis would be fairly easy for people to do
If anyone living in the Cairns area can obtain the seeds and distribute some
it would be a service to mankind to help thwart the over commercial
exploitation of this natural resource, or worse still the total suppression
of the treatment.
The company plans to eventually sell the drug patents to a big multinational
pharma company, and make money from selling out in this way which is clearly
outlined in the investor presentation on the company website.
http://www.qbiotics.com/?gclid=CIuykNL_nqICFQcYewodnxa8yA#//
Thus there will be no cheap or widespresd access to this treatment, but just
another rip off with the drug being sold for many thousands of dollars a
dose.
An effective dose is 3mg and the company has stockpiled 12,000 doses for
trials, which it values at betweem 3 and 5 million dollars, but has not
decided on the commercial marketing cost for vetinary applications.
The company CEO states that the active ingredient is a "major component" of
the seed of the plant (which she refers to by the name "Fontania" (phonetic
spelling from the audio on a film clip) but which news sources state to be
the Blushwood and the photo of the seeds on the company website look like
Blushwood seeds.
It is further stated in Qbiotics promotional literature that the active
ingredient is able to be easily isolated, however if it is a major component
of the seed, and from the dosage used 3mg, it may not need to be actually
isolated at all to be effective. Hence my earlier comment that a tincture in
say 60% alcohol of the seeds may be a simple and effective treatment?
It is applied both topically and injected into solid tumors with dramatic
results. See the company website above.
Any one around Cairns with a half dead dog cat or horse, want to gather up
some seeds, soak them in alcohol, and apply the tincture to to an external
tumor or inject a small quantity into a solid tumor? With an animal thats
going to die of cancer anyway soon what have you got to loose?
And there can't be much harm in anyone trying such a tincture on solar
keritosis or Basal cells and see what happens?